20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1176 | Racecadotril | Acetorphan | Neprilysin , Proteasome |
Racecadotril (Acetorphan) has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis. | |||
T7693 | Thiorphan | Neprilysin | |
Thiorphan is an neprilysin inhibitor (NEP; IC50 : 0.007 μM). | |||
TQ0106 | Sacubitrilat | LBQ-657 | Neprilysin |
Sacubitrilat (LBQ-657) (LBQ657) is an effective inhibitor of active neprilysin (NEP). | |||
T4574 | Sacubitril | AHU 377,AHU377,AHU-377 | Neprilysin |
Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. | |||
T4200 | Sacubitril hemicalcium salt | AHU-377 (hemicalcium salt),AHU377 calcium salt | Neprilysin |
Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ... | |||
T2318 | Sacubitril/Valsartan | Sacubitril mixture with Valsartan,Valsartan,Sacubitril,LCZ696 | Apoptosis , RAAS , Neprilysin |
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure. | |||
T6627 | Phosphoramidon Disodium | Phosphoramidon Disodium Salt | RAAS , Neprilysin , Others |
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. | |||
T10918 | NEP-IN-1 | Neprilysin | |
NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders. | |||
T19626 | LHW090-A7 | Neprilysin | |
LHW090-A7 is an neutral endopeptidase (NEP) inhibitor, and an enzyme responsible for the metabolic inactivation of enkephalins. | |||
T27119L | (Rac)-Daglutril | SLV 306 acetic acid,2-((3S)-3-(1-(2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentane-1-carboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid | Others |
(Rac)-Daglutril (SLV 306 acetic acid) is the racemate form of Daglutril. Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential ... | |||
TP1917L1 | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base) | Bradykinin Receptor |
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cl... | |||
T1168 | Desonide | Tridesilon,Locapred,Prednacinolone | Glucocorticoid Receptor |
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ... | |||
T10671 | Candoxatril | UK 79300 | Others |
Candoxatril is an inhibitor neutral endopeptidase (NEP). | |||
T23698 | Aladotril | BP1137,BP 1137,BP-1137 | |
Aladotril is an inhibitor of neutral endopeptidase. Its prodrug is aladotrilat. | |||
T23699 | Aladotrilat | Fasidotrilat | |
Aladotrilat is an inhibitor of neutral endopeptidase. Its prodrug is aladrotril. | |||
T15696 | NEP-IN-2 | Others | |
NEP-IN-2 is an inhibitor of neutral endopeptidase. It also is used in the research of proliferation in atherosclerosis, restenosis. | |||
T28715 | Sch 34826 | Sch34826,Sch-34826 | |
Sch 34826 is a potent, selective neutral endopeptidase inhibitor. | |||
T12994 | SQ28603 | Squibb 28603,SQ28,603 | Others |
SQ28603 is a potent and selective neutral endopeptidase 3.4.24.11 (NEP) inhibitor. | |||
T70567 | CGS 25462 | ||
CGS 25462 is a neutral endopeptidase (NEP) inhibitor. | |||
T31598 | Ecadotril | S.049,BAY-y 7432,BAY y 7432,BP 1.02,S049 | |
Ecadotril is a neutral endopeptidase (NEP) inhibitor, which plays an anti hypertensive role. |